Interleukine 22

[Interleukine-3: a multifunctional cytokine].

Normal hematopoiesis is regulated in part by a variety of growth factors (HGF) acting at different stages of cellular maturation. Among the HGF acting on early progenitors, Interleukin-3 (IL-3) is one of the first well characterized. This cytokine exhibits various biological activities including proliferative effects on hematopoietic stem cells as well as regulatory properties on mature element...

IL 22 ( interleukin 22 )

A22 22..22

Four randomised controlled trials (RCTs) and one RCT metaanalysis are featured in the Journal this month. The latter is a review of trials of newer-generation antidepressants and cognitive–behavioural therapy (CBT) for adolescent depression (Dubicka et al, pp. 433–440). In an area of clinical practice plagued by controversy, the authors of this review were able to contribute the finding that ad...

A22 22..22

Three papers in the Journal this month consider issues related to measuring, understanding and treating mental ill health in childhood. Baron-Cohen et al (pp. 500–509) undertook a study to establish the prevalence of autism-spectrum conditions in Cambridgeshire using two case ascertainment methods. First, a survey of individuals on the Special Educational Needs register and second, a screening ...

Absolute quantification of murine interleukine-4, interleukine- 10 and interferon-γ gene transcripts using Real Time PCR

The study of cytokines gene expression is quite important in various conditions of health and disease for the evaluation of clinical responses to new vaccination approaches. An absolute quantification is based on a calibration curve and production of standard controls to achieve more reliable results than in relative system. In this study we attempted to construct standard controls to evaluate ...